All You Need to Know Before you Buy Palmitoylethanolamide in Australia

What is Palmitoylethanolamide?

Palmitoylethanolamide (PEA) is an endocannabinoid (a cannabinoid produced in the body) that helps repair damaged cells and meliorate the activities of overbearing cells. It has a structure that’s similar to those of cannabinoids found in cannabis including THC and CBD and also acts on similar receptor systems. However, it doesn’t induce the psychoactive effects that are associated with cannabis cannabinoids. It’s a biologically active lipid that can regulate the activities of cannabinoid receptors and inflammatory cells. PEA is also abundantly present in plant and animal sources like meat, eggs, veggies, soybeans, potatoes, etc.

PEA has been around for decades and has undergone myriads of clinical trials that have verified its various medicinal potentials. Specifically, its neuroprotective, anti-inflammatory and anti-nociceptive properties have been shown to boost the body’s recovery from a vast range of ailments.

These studies also show that the drug is one of the most effective natural painkillers and that it can also contribute to the regulation of a wide range of cellular activities, especially those associated with chronic diseases.

How Does Palmitoylethanolamide Work?

PEA helps to regulate a wide array of cellular activities (especially those known as ‘inflammatory mediators’) to restore normalcy in people grappling with pain and inflammation. It’s applicable to a wide range of chronic ailments thanks to a medicinal profile that embodies anti-inflammatory, anti-nociceptive, and anti-convulsing properties.

The significantly lower quantities of the substance in people with chronic illnesses and pains point to its significance in the body’s responses to these ailments. In light of this discovery, several clinical studies have verified that the body is better off against chronic illnesses and pains when it’s supplied with supplementary doses of PEA.

In other words, the substance works by regulating cellular activities that generate chemicals and signals that trigger the perception of pain and discomfort in the body. One of such chemical activities is that of a cell group called “Mast cells”, which give rise to the production of histamines, which cause muscle contractions and the dilation of capillaries.

Despite possessing chemical structures that are similar to that of THC and also interacting with similar receptor systems, PEA isn’t treated in any way similar to THC by Australia’s drug use Law. It’s neither intoxicating nor addictive, and doesn’t have any known major side effects. And unlike THC and other cannabinoids in cannabis, PEA has been conclusively proven in hundreds of studies to be medicinally beneficial in the treatment of a wide range of cases.

PEA is perfectly legal in Australia, since it has been scientifically proven to render therapeutic benefits. And since it has no known side effects, doesn’t interact negatively with other drugs, and the body is tolerant to it even in significantly high doses, you don’t need a doctor’s prescription or supervision to take the substance safely.

Pros and Cons of Palmitoylethanolamide 

PEA is at the heart of cellular functions that regulate the body’s perception of pain and discomfort. src


  • Given the ubiquity of its function in the body, it can help the body fight a vast range of ailments, including osteoarthritis, lower back pain, shingles, depression, autism, peripheral neuropathy, fibromyalgia, failed back surgery syndrome, dental pains, neuropathic pain in stroke and multiple sclerosis, chronic regional pain syndrome, chronic pelvic pain, postherpetic neuralgia, and vaginal pains.
  • Unlike medical cannabis products, PEA is totally free of any psychoactive characteristics. It’s therefore an ideal alternative for people who’re averse to the mind-altering effects of cannabis products.
  • Since it doesn’t interact negatively with other drugs, it’s safe to use in combination with other pain medications and treatment regimens. Studies show that it can also enhance the body’s response to other medications.
  • It’s well-tolerated in the body, so you don’t have to worry much about overdosing. You can take as much as you want depending on your body’s needs.
  • You also don’t need a doctor’s prescription nor supervision to use the substance effectively. Unlike other prescription drugs, PEA can save you $100’s of a doctor’s consultation and prescription fees.


  • There are currently no known downsides of using the drug since it’s a compound that’s already present in nearly every cell and tissue in the body. At worst, you might feel mild side effects like stomach cramps and diarrhea resulting from other additives in a particular PEA product.

Published by Neil

Neil believes Cannabis has medical benefits and should be prescribed by a Doctor. This site aims to provide accurate information on the science and legality of Cannabis so you can make informed decisions.

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